V-PLEX Mouse IL-23 Kit

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Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the  U-PLEX Mouse IL-23 Assay.

V-PLEX Mouse IL-23 Kit Overview
The V-PLEX Mouse IL-23 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse IL-23 Kit enables the sensitive detection of IL-23 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse IL-23 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.

V-PLEX Mouse IL-23 Assay Features
  • Validated to measure mouse IL-23 in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 0.899 – 7,600 pg/mL
  • LLOQ: 4.19 pg/mL

Typical Data
Calibration curve for the V-PLEX Mouse IL-23 Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Mouse IL-23 Kit Calibration Curve
Calibration Curve for V-PLEX Mouse IL-23 Kit
IL-23 Analyte

Description - Mouse IL-23 (IL-12B) is a heterodimer composed of the p40 protein that is shared with IL-12, and p19, which belongs to the IL-6 superfamily. IL-23 is secreted by dendritic cells and macrophages, is involved in Th17 cell differentiation in a pro-inflammatory setting, and induces proliferation of memory T cells.

Disease Research Area - Autoimmune & Inflammation, Metabolic Diseases, Oncology

Application Area - Cytokines & Chemokines, Inflammatory Injury

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