V-PLEX Human IL-22 Kit


V-PLEX Human IL-22 Kit Overview
The V-PLEX Human IL-22 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Human IL-22 Kit enables the sensitive detection of native IL-22 in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Human IL-22 assay is available as an individual assay kit as well as in a multiplex combination with other TH17-related analytes in the V-PLEX TH17 Panel 1 (human) Kit (catalog # K15085G, K15085D).

V-PLEX Human IL-22 Assay Features
  • Validated to measure human IL-22 in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.270 pg/mL – 325 pg/mL
  • LLOQ: 2.78 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Human IL-22 assay were assessed and representative data are presented below.

Figure 1. V-PLEX Human IL-22 Calibration Curve
Human IL-22 Calibrator Curve
Figure 2. V-PLEX Human IL-22 Data
Human IL-22 Calibrator Curve Data
IL-22 Analyte

Description - Interleukin-22 (IL-22), first described as IL-10-related T cell inducible factor, is part of the IL-10 superfamily notable for its proinflammatory or anti-inflammatory actions, which are dependent on the context of its expression. It is produced by TH17 cells and NK cells, and especially in epithelial cells found in the skin, lung, liver, and intestine. IL-22 binds heterodimer IL-22R that is made up of IL-22R1 and IL-10R2.

Disease Focus - Rheumatoid arthritis, dermal inflammation, acanthosis, psoriasis, and atopic dermatitis.

Application Area - Inflammation, cytokines and chemokines

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1 plate
5 plates
25 plates
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