V-PLEX Human IL-1RA Kit


V-PLEX Human IL-1RA Kit Overview
The V-PLEX Human IL-1RA Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Human IL-1RA Kit enables the sensitive detection of native IL-1RA in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Human IL-1RA assay is also available in a multiplex combination with other related cytokines in the V-PLEX Cytokine Panel 2 (human) Kit (catalog # K15084G, K15084D).

V-PLEX Human IL-1RA Assay Features
  • Validated to measure human IL-1RA in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 1.12 pg/mL – 650 pg/mL
  • LLOQ: 9.19 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Human IL-1RA assay were assessed and representative data are presented below.

Figure 1. V-PLEX Human IL-1RA Calibration Curve
Human IL-1RA Calibrator Curve
Figure 2. V-PLEX Human IL-1RA Data
Human IL-1RA Calibrator Curve Data
IL-1RA Analyte

Description - Human interleukin 1 receptor antagonist (IL1RN, IL1F3, IL1RA, IRAP; Gene ID: 3557) is a protein that is produced in at least two forms, one that stays inside the cell and one that is secreted. This assay is for the secreted version. IL-1RA is secreted by various cell types including epithelial cells, monocytes, and adipocytes. It binds to the IL-1 receptor thus preventing signaling by both IL-1α and IL 1β cytokines.

Disease Research Focus - Asthma and various autoimmune disorders.

Application Area - Inflammation, cytokines, and chemokines

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1 plate
5 plates
25 plates
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