V-PLEX Human IL-17A Gen. B Kit, SECTOR (1 PL)

V-PLEX Human IL-17A Gen. B Kit Overview
The V-PLEX Human IL-17A Gen. B Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Human IL-17A Gen. B Kit enables the sensitive detection of native IL-17A in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Human IL-17A Gen. B assay is available as an individual assay kit as well as in a multiplex combination with other TH17-related analytes in the V-PLEX TH17 Panel 1 (human) Kit (catalog # K15085G, K15085D).

V-PLEX Human IL-17A Gen. B Assay Features
  • Validated to measure human IL-17A in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.413 pg/mL – 1,950 pg/mL
  • LLOQ: 5.86 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Human IL-17A Gen. B assay were assessed and representative data are presented below.

Figure 1. V-PLEX Human IL-17A Gen. B Calibration Curve
Human IL-17A Calibrator Curve
Figure 2. V-PLEX Human IL-17A Gen. B Data
Human IL-17A Calibrator Curve Data
IL-17A Analyte

Description - Interleukin-17 (IL-17) cytokines are emerging as key regulators of initiation and maintenance of the proinflammatory immune response. The family consists of six related molecules: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F. These molecules have a molecular mass of 20–30 kDa and share 20–50% homology to IL-17A. In general, IL-17 induces several pro-inflammatory molecules such as IL-6, IL-8, GM-CSF, IL-1, TNF-α, and MCP-1 from different cell types including fibroblasts, endothelial cells, epithelial cells, and tissue-specific macrophages. Differences in expression patterns and production levels appear to give specificity of action and role to each of the IL-17 family members.

Disease Focus - Inflammatory diseases, including rheumatoid arthritis, asthma, lupus, allograft rejection, and tumorigenicity.

Application Area - Inflammation, cytokines and chemokines

  • Specifications
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Order Details
Catalog No
Size
Price in USD
Qty
K151WMD-1
1 plate
$371.00
K151WMD-2
5 plates
$1,577.00
K151WMD-4
25 plates
$6,493.00
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