V-PLEX Human IL-17A/F Kit


V-PLEX Human IL-17A/F Kit Overview
The V-PLEX Human IL-17A/F Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Human IL-17A/F Kit enables the sensitive detection of native IL17A/F in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Human IL-17A/F assay is available as an individual assay kit as well as in a multiplex combination with other related cytokines in the V-PLEX Cytokine Panel 2 (human) Kit (catalog # K15084G, K15084D).

V-PLEX Human IL-17A/F Assay Features
  • Validated to measure human IL-17A/F in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.930 pg/mL – 3,900 pg/mL
  • LLOQ: 7.57 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Human IL-17A/F Assay were assessed and representative data are presented below.

Figure 1. V-PLEX Human IL-17A/F Calibration Curve
Human IL-17A/F Calibrator Curve
Figure 2. V-PLEX Human IL-17A/F Data
Human IL-17A/F Calibrator Curve Data
IL-17A/F Analyte

Description - Human IL-17A/F [Gene ID: 3605 (IL-17A), 112744 (IL-17F)] is a cross-linked heterodimer composed of IL-17A (CTLA8) and IL-17F proteins that is secreted by IL-23 activated TH17 cells. IL-17A and IL-17F are both prototypical of the IL-17 family of cytokines. IL-17A/F binds to IL-17RA and recruits neutrophils with intermediate potency between IL-17A and IL-17F homodimers.

Disease Research Area - Autoimmune and inflammatory diseases including asthma, rheumatoid arthritis, and inflammatory bowel disease (IBD).

Application Area - Inflammation, cytokines, and chemokines

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1 plate
5 plates
25 plates
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