Human granulocyte-macrophage colony stimulating factor (GM-CSF), also known as colony-stimulating factor (CSF), is a glycosylated 16.3 kDa protein with two internal disulfide bonds. It is involved in the stimulation of growth and differentiation of hematopoietic precursor cells in response to inflammatory stimuli. It is also involved in dendritic cell differentiation, negative regulation of apoptotic process, and positive regulation of IL-23 production and tyrosine phosphorylation of STAT5 protein. GM-CSF has been shown to reduce chemotherapy-induced neutropenia in different types of cancers. It is involved in a number of disorders including autoimmune and inflammatory diseases. The Human GM-CSF Kit provides assay-specific components for the quantitative determination of endogenous GM-CSF in human urine, serum, plasma, and cell culture supernatants.
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Specifications
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Kit Contents
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References
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Documentation
Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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GM-CSF
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Species
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Human
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Instrument
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MESO QuickPlex SQ 120
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SECTOR Imager 2400
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SECTOR Imager 6000
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MESO SECTOR S 600
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Plate Type
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96-well
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Rat Monoclonal
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LLOD (Sensitivity)
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0.14 pg/mL
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Dynamic Range
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0.14–750 pg/mL
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Sample Type
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Serum, Plasma, Urine, Cell Culture Supernatant
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Recombinant standards
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Expressed in E. coli
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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1 vial (1 vial)
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2-8°C
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1 vial (75 μL)
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Human GM-CSF Plate
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2-8°C
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1 each (1 each)
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Diluent Assembly 3 (includes Diluent 3 - 5 mL, and Diluent 43 - 10 mL)
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≤-10°C
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1 each
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RT
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1 each (50 mL)
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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5 vial (1 vial)
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2-8°C
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1 vial (375 μL)
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Human GM-CSF Plate
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2-8°C
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5 each (1 each)
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Diluent Assembly 4 (includes Diluent 3 - 25 mL, and Diluent 43 - 50 mL)
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≤-10°C
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1 each
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RT
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1 each (50 mL)
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Product Description
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Storage
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Quantity per Kit
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2-8°C
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25 vial (1 vial)
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2-8°C
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5 vial (375 μL)
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Human GM-CSF Plate
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2-8°C
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25 each (1 each)
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Diluent Assembly 4 (includes Diluent 3 - 25 mL, and Diluent 43 - 50 mL)
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≤-10°C
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5 each
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RT
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5 each (50 mL)
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Title
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Journal
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Year
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Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy
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Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
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Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
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Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report.
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Effect of short-term pair housing of juvenile Rhesus Macaques (Macaca mulatta) on immunologic parameters.
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View All
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Product Inserts
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Product Highlights
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Certificate of analysis
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View More
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SDS
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Kit Layout (Add-in)
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters