U-PLEX Mouse IL-4 Assay


MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Mouse interleukin-4 (IL-4), also known as B-cell stimulatory factor 1 (BSF-1) and lymphocyte stimulatory factor 1, is a glycosylated 15.8 kDa protein with three intra-chain disulfide bonds. It is produced by Th2 cells and participates in activation of B-cells and other cell types. It also stimulates DNA synthesis and enhances the expression of IgE and IgG1. IL-4 decreases the production of Th1 cells, macrophages, IFN-γ, and IL-12. It is associated with severe asthma among other disorders. The U-PLEX Mouse IL-4 Assay provides the components for the quantitative determination of both natural and recombinant IL-4 in serum, plasma, and cell culture supernatants.

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1 plate
5 plates
25 plates
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