U-PLEX Mouse IL-23 Assay


U-PLEX Mouse IL-23 Assay Overview
The U-PLEX Mouse IL-23 Assay maximizes your flexibility to design an experiment that measures IL-23 alone or multiplexed with MSD U-PLEX assays, your own antibody pairs, or a combination of both. U-PLEX assays demonstrate high sensitivity, excellent precision, and up to 5-logs of linear dynamic range. Plates are read in less than 90 seconds on any MSD instrument, using no complicated fluidics or calibration procedures.

U-PLEX Mouse IL-23 Assay Features
  • Simple protocol similar to ELISAs, yet uses less sample
  • Measures mouse IL-23 in serum, plasma, and cell culture supernatants
  • Create custom multiplexes using a selection of U-PLEX assays, your own antibody pairs or both

Assay Format
  • Singleplex – includes MSD GOLD Small Spot Streptavidin Plates
  • Multiplex – includes U-PLEX multiplex plates
  • Both formats use the same assay components for efficient transfer between single- and multiplex configurations.

IL-23 Analyte
Description- Mouse IL-23 (IL-12B) is a heterodimer composed of the p40 protein that is shared with IL-12*, and p19, which belongs to the IL-6 superfamily. IL-23 is secreted by dendritic cells and macrophages, is involved in TH17 cell differentiation in a pro-inflammatory setting, and induces proliferation of memory T-cells.

Disease Focus - Crohn’s disease and other autoimmune disorders including psoriasis, inflammatory bowel disease and certain tumors.

*NOTE: The U-PLEX Mouse IL-23 assay should not be combined in the same plate with U-PLEX Mouse IL-12p70 due to cross reactivity of the p40 protein.

  • Specifications
  • Kit Contents
  • References
  • Documentation
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Price in USD
1 plate
5 plates
25 plates
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