U-PLEX Human TGF-β1 Assay Overview
The U-PLEX Human TGF-β1 Assay maximizes your flexibility to design an experiment that measures TGF-β1 alone or multiplexed with other MSD U-PLEX assays, your own antibody pairs, or a combination of both. This assay accurately quantitates native and recombinant human TGF-β1 in multiple sample types. To learn more about the advantages of U-PLEX assays
click here.
U-PLEX Human TGF-β1 Assay Features
- Measures human TGF-β1 in serum, plasma, and cell culture supernatants
- Dynamic range: 9.1 pg/mL – 37,000 pg/mL
- LLOD: 9.1 pg/mL
Typical Data
Calibration curve accuracy and precision for the U-PLEX Human TGF-β1 assay were assessed and representative data are presented below.
Figure 1. U-PLEX Human TGF-β1 Calibration Curve
Figure 2. U-PLEX Human TGF-β1 Data
TGF-β1 Analyte
Description - Human transforming growth factor β1 (TGFbeta, TGFB1, CED, DPD1; Gene ID: 7040) is a member of at least three ligands in the TGF family that are highly pleiotropic and potent cytokines. They are secreted by almost all cell types, and as such their activity is tightly controlled. TGFs are secreted and complexed with two other proteins, LAP and TGFBP, and require proteolytic cleavage to be active. TGFs are highly conserved. TGFs regulate T cell maturation and differentiation and inhibit B cell proliferation.
Disease Focus/Application Area - Cancer, Marfan syndrome, kidney disease, diabetes, and multiple sclerosis.
-
-
Specifications
-
Kit Contents
-
References
-
Documentation
|
Application(s)
|
|
Cytokines & Chemokines
,
Immunology/Inflammation
|
|
Analyte(s)
|
|
TGF-β1
|
|
Species
|
|
Human
|
|
Instrument
|
|
MESO QuickPlex SQ 120
,
SECTOR Imager 2400
,
SECTOR Imager 6000
,
MESO SECTOR S 600
|
|
U-PLEX Group Compatibility
|
|
Biomarker Group 2
|
|
Plate Type
|
|
96-well
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
Detection Antibody
|
|
Chicken Polyclonal
|
|
Dynamic Range
|
|
9.1 - 37,000 pg/mL
|
|
Sample Type
|
|
Serum, Plasma, Cell Culture Supernatant
|
|
LLOD (Sensitivity)
|
|
9.1 pg/mL
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Statement(s)
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
Storage Condition
|
|
Multi-Component
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
1 ea
(1 plate size)
|
|
|
|
|
2-8°C
|
1 vial
(1 vial)
|
|
|
|
|
2-8°C
|
1 ea
(1 plate)
|
|
|
|
|
2-8°C
|
1 ea
(50 mL)
|
|
|
|
|
≤-10°C
|
1 Bottle
(10 mL)
|
|
|
|
|
≤-10°C
|
1 ea
(8 mL)
|
|
|
|
|
RT
|
1 ea
(50 mL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
1 ea
(5 plate size)
|
|
|
|
|
2-8°C
|
5 vial
(1 vial)
|
|
|
|
|
2-8°C
|
5 ea
(1 plate)
|
|
|
|
|
2-8°C
|
1 ea
(50 mL)
|
|
|
|
|
≤-10°C
|
1 Bottle
(50 mL)
|
|
|
|
|
≤-10°C
|
1 ea
(40 mL)
|
|
|
|
|
RT
|
1 ea
(50 mL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
5 ea
(5 plate size)
|
|
|
|
|
2-8°C
|
25 vial
(1 vial)
|
|
|
|
|
2-8°C
|
25 ea
(1 plate)
|
|
|
|
|
2-8°C
|
5 ea
(50 mL)
|
|
|
|
|
≤-10°C
|
5 Bottle
(50 mL)
|
|
|
|
|
≤-10°C
|
5 ea
(40 mL)
|
|
|
|
|
RT
|
5 ea
(50 mL)
|
|
|
|
Title
|
Journal
|
Year
|
|
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
|
|
|
|
|
|
|
Product Inserts
|
|
|
|
Product Highlights
|
|
|
|
SDS
|
|
|
|
Datasheets
|
|
|
Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters