U-PLEX Chemokine Combo Mouse


U-PLEX Chemokine Combo (ms) Overview
The U-PLEX Chemokine Combo (ms) contains 7 chemokines grouped together for ordering convenience. This assay accurately quantitates 7 native and recombinant mouse Chemokine biomarkers in multiple sample types. To learn more about the advantages of U-PLEX assays click here.

U-PLEX Chemokine Combo (ms) Features
  • Measures 7 mouse biomarkers in serum, plasma, and cell culture supernatants
  • Create custom analyte subsets via the U-PLEX Assay Designer
  • LLODs range from 0.10 pg/mL to 13 pg/mL

Typical Data
Calibration curve accuracy and precision for each analyte in the U-PLEX Chemokine Combo (ms) were assessed in multiplex format. Representative data are presented below.

Figure 1. U-PLEX Chemokine Combo (ms) Data
Mouse Chemokine Combo Data
U-PLEX Chemokine Combo (ms)

Description - Chemokines are small chemotactic cytokines with molecular weights around 8–10 kDa that are capable of inducing directed chemotaxis. Four cysteine residues in conserved locations result in a compact 3-dimensional structure. Based on the spacing of the first two cysteine residues, chemokines are divided into four families: CC chemokines, CXC chemokines, C chemokines, and CX3C chemokines, where C represents cysteine and X represents any other amino acid. Chemokines function by activating specific G protein-coupled receptors resulting in migration of inflammatory and non-inflammatory cells. The proinflammatory chemokines are responsible for migration of immune cells to the infection site, while the homeostatic chemokines are responsible for recruiting cells for tissue maintenance and development.

Disease Focus/Application Area - Infections; tissue repair and development.

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1 plate
5 plates
25 plates
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