R-PLEX Rat MCP-1 Antibody Set Overview The R-PLEX Rat MCP-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MCP-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Rat MCP-1 Antibody Set Features - Measures rat MCP-1 in Serum, Plasma
- Dynamic range: 0.59 - 4,000 pg/mL
- Median LLOD: 0.59 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Rat MCP-1 Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Rat MCP-1 Antibody Set Calibration Curve 
MCP-1 Analyte
Description - Monocyte Chemoattractant Protein 1 (MCP-1, CCL2, GDCF-2, HC11, SCYA2, MCP1) is a C-C motif chemokine ligand 2 that is secreted primarily by monocytes and macrophages, but also by neurons, astrocytes, and glial cells. It is chemotactic for basophils and monocytes. MCP-1 is involved in monocytic accumulations like psoriasis and rheumatoid arthritis, and in Alzheimer’s, traumatic brain injury, and epilepsy.
Application Area - Cardiovascular Disease, Neurodegenerative
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Recommended Components
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Specifications
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Kit Contents
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References
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Documentation
You will need plates, diluents, and read buffer to run your assay. Please select from the below menu.
R-PLEX Sets are intended to be used with other MSD components such as plates, diluents and MSD Read Buffer. If you don’t already have these items, you can purchase them along with your Antibody Set(s). The “Recommended Components” tab provides helpful suggestions or you can call MSD Customer Service (Phone number) for assistance. R-PLEX Sets can also be used with other antibody sets such as U-PLEX antibody sets (make a link to UPLEX landing page) for multiplex measurements.
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Cardiovascular
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Neurobiology/Neurodegen.
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Immunology/Inflammation
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Analyte(s)
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MCP-1
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Species
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Rat
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Capture Antibody
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Goat Polyclonal
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Detection Antibody
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Goat Polyclonal
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Dynamic Range
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0.59-4000 pg/mL
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Sample Type
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Serum, Plasma
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Recombinant standards
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Recombinant Expressed in mouse myeloma cell line, NS0
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LLOD (Sensitivity)
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0.59 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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24770
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UniProt ID(s)
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P14844
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Assay Diluent(s)
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Diluent 42
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Antibody Diluent(s)
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Diluent 40
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Product Description
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Storage
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Quantity per Kit
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Rat MCP-1 Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Rat MCP-1 Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Rat MCP-1 Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Rat MCP-1 Calibrator
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≤-70°C
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50 vial
(1 vial)
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Title
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Journal
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Year
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CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer’s disease
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Kinetics and Biomarkers of Severe Cytokine Release Syndrome after CD19 Chimeric Antigen Receptor-modified T Cell Therapy.
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Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.
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Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
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Product Inserts
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Product Highlights
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SDS
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Handouts
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Datasheets
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