R-PLEX Rat MCP-1 Antibody Set Overview The R-PLEX Rat MCP-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MCP-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Rat MCP-1 Antibody Set Features - Measures rat MCP-1 in Serum, Plasma
- Dynamic range: 0.59 - 4,000 pg/mL
- Median LLOD: 0.59 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Rat MCP-1 Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Rat MCP-1 Antibody Set Calibration Curve 
MCP-1 Analyte
Description - Monocyte Chemoattractant Protein 1 (MCP-1, CCL2, GDCF-2, HC11, SCYA2, MCP1) is a C-C motif chemokine ligand 2 that is secreted primarily by monocytes and macrophages, but also by neurons, astrocytes, and glial cells. It is chemotactic for basophils and monocytes. MCP-1 is involved in monocytic accumulations like psoriasis and rheumatoid arthritis, and in Alzheimer’s, traumatic brain injury, and epilepsy.
Application Area - Cardiovascular Disease, Neurodegenerative
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Recommended Components
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Specifications
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Kit Contents
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References
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Resources
You will need plates, diluents, and read buffer to run your assay.
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Catalog No.
Product Name
Size
L45SA-1
R50AA-4
R92TG-3
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Application(s)
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Cardiovascular
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Neurobiology/Neurodegen.
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Immunology/Inflammation
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Analyte(s)
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MCP-1
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Species
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Rat
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Capture Antibody
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Goat Polyclonal
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Detection Antibody
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Goat Polyclonal
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Dynamic Range
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0.59-4000 pg/mL
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Sample Type
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Serum, Plasma
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Recombinant standards
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Recombinant Expressed in mouse myeloma cell line, NS0
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LLOD (Sensitivity)
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0.59 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID
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24770
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UniProt ID
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P14844
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Assay Diluent(s)
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Diluent 42
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Antibody Diluent(s)
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Diluent 40
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Product Description
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Storage
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Quantity per Kit
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Rat MCP-1 Antibody Set (5 Plate Size)
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2-8°C | 1 ea
(5 plate size) |
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Rat MCP-1 Calibrator
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≤-70°C | 5 vial
(1 vial) |
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Product Description
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Storage
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Quantity per Kit
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Rat MCP-1 Antibody Set (5 Plate Size)
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2-8°C | 10 ea
(5 plate size) |
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Rat MCP-1 Calibrator
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≤-70°C | 50 vial
(1 vial) |
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Title
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Journal
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Year
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CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer’s disease
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Kinetics and Biomarkers of Severe Cytokine Release Syndrome after CD19 Chimeric Antigen Receptor-modified T Cell Therapy.
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Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.
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Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
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SDS
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Handouts
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Datasheets
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