R-PLEX Rat MCP-1 Antibody Set Overview The R-PLEX Rat MCP-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MCP-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Rat MCP-1 Antibody Set Features - Measures rat MCP-1 in Serum, Plasma
- Dynamic range: 0.59 - 4,000 pg/mL
- Median LLOD: 0.59 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data Calibration curve for the R-PLEX Rat MCP-1 Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Rat MCP-1 Antibody Set Calibration Curve 
MCP-1 Analyte
Description - Monocyte Chemoattractant Protein 1 (MCP-1, CCL2, GDCF-2, HC11, SCYA2, MCP1) is a C-C motif chemokine ligand 2 that is secreted primarily by monocytes and macrophages, but also by neurons, astrocytes, and glial cells. It is chemotactic for basophils and monocytes. MCP-1 is involved in monocytic accumulations like psoriasis and rheumatoid arthritis, and in Alzheimer’s, traumatic brain injury, and epilepsy.
Application Area - Cardiovascular Disease, Neurodegenerative
-
Recommended Components
-
Specifications
-
Kit Contents
-
References
-
Documentation
Why do I need other components
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
|
Application(s)
|
|
Cardiovascular
,
Neurobiology / Neurodegeneration
,
Immunology/Inflammation
|
|
|
Analyte(s)
|
|
MCP-1
|
|
|
Species
|
|
Rat
|
|
|
Capture Antibody
|
|
Goat Polyclonal
|
|
|
Detection Antibody
|
|
Goat Polyclonal
|
|
|
Dynamic Range
|
|
0.59-4000 pg/mL
|
|
|
Sample Type
|
|
Serum, Plasma
|
|
|
Recombinant standards
|
|
Recombinant Expressed in mouse myeloma cell line, NS0
|
|
|
LLOD (Sensitivity)
|
|
0.59 pg/mL
|
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
|
Storage Statement(s)
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
|
Storage Condition
|
|
Multi-Component
|
|
|
Gene ID(s)
|
|
24770
|
|
|
UniProt ID(s)
|
|
P14844
|
|
|
Assay Diluent(s)
|
|
Diluent 42
|
|
|
Antibody Diluent(s)
|
|
Diluent 40
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Rat MCP-1 Antibody Set (5 Plate Size)
|
2-8°C
|
1 ea
(5 plate size)
|
|
|
|
Rat MCP-1 Calibrator
|
≤-70°C
|
5 vial
(1 vial)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Rat MCP-1 Antibody Set (5 Plate Size)
|
2-8°C
|
10 ea
(5 plate size)
|
|
|
|
Rat MCP-1 Calibrator
|
≤-70°C
|
50 vial
(1 vial)
|
|
|
|
Title
|
Journal
|
Year
|
|
CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer’s disease
|
|
|
|
Kinetics and Biomarkers of Severe Cytokine Release Syndrome after CD19 Chimeric Antigen Receptor-modified T Cell Therapy.
|
|
|
|
Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
|
|
|
|
Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.
|
|
|
|
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
|
|
|
|
|
View All
|
|
Product Inserts
|
|
|
|
Product Highlights
|
|
|
|
SDS
|
|
|
|
Handouts
|
|
|
|
Datasheets
|
|
|
Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters