R-PLEX Rat IL-5 Antibody Set

R-PLEX Rat IL-5 Antibody Set Overview
The R-PLEX Rat IL-5 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of IL-5 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat IL-5 Antibody Set Features
  • Measures rat IL-5 in serum and plasma
  • Dynamic range: 0.08 - 4,500 pg/mL
  • Median LLOD: 0.08 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat IL-5 Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Rat IL-5 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Rat IL-5 Antibody Set
IL-5 Analyte

Description - Interleukin-5 (IL-5, B-cell growth factor II, BCGF-II, T-cell replacing factor, TRF) is a glycosylated homodimer that is mainly produced by eosinophils and Th2 cells. It induces terminal differentiation of late-developing B cells to immunoglobulin-secreting cells. IL-5 binds to the α subunit of the receptor, which then associates with the βc subunit, yielding a high affinity interaction. IL-5 is associated with eosinophilia, atopic dermatitis, and pulmonary fibrosis along with other disorders.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunology/Inflammation

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5 plate size
50 plate size
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