R-PLEX Human Serpin A1 Antibody Set

R-PLEX Human Serpin A1 Antibody Set Overview
The R-PLEX Human Serpin A1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Serpin A1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Serpin A1 Antibody Set Features
  • Measures human Serpin A1 in Serum, Plasma, CSF
  • Dynamic range: 3.8 - 300,000 pg/mL
  • Median LLOD: 3.8 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Serpin A1 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Serpin A1 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Serpin A1 Antibody Set
Serpin A1 Analyte

Description - Serpin A1 (PI, A1A, AAT, PI1, PRO2275, α1AT, α-1-anti-trypsin) is primarily produced by the liver and inhibits a wide variety of proteases including bacterial proteases. The concentration of serpin A1 in plasma can rise significantly in acute inflammation. Its absence is associated with COPD and emphysema. It may play a role in the suppression of cancer cell growth. Differentially sialylated forms of serpin A1 have been associated with dementia caused during Alzheimer's disease and Parkinson's disease.

Application Area - Autoimmune and Inflammation, Liver and Kidney Disease,

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5 plate size
50 plate size
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