R-PLEX Human SCFR/Kit Antibody Set

R-PLEX Human SCFR/Kit Antibody Set Overview
The R-PLEX Human SCFR/Kit Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of SCFR/Kit in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human SCFR/Kit Antibody Set Features
  • Measures human SCFR/Kit in serum and plasma
  • Dynamic range: 2.0 - 40,000 pg/mL
  • Median LLOD: 2.0 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human SCFR/Kit Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human SCFR/Kit Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human SCFR/Kit Antibody Set
SCFR/Kit Analyte

Description - Stem Cell growth Factor Receptor (SCFR, Kit, c-Kit, CD117, PBT) is a receptor tyrosine kinase that binds mast cell growth factor. It is expressed mostly on the surface of hematopoietic stem cells. SCFR/Kit activates pathways that influence cell survival, proliferation, and differentiation. SCFR is a proto-oncogene that drives the development of certain leukemias and gastrointestinal stromal tumors (GISTs). Activation of SCFR can be used to mobilize hematopoietic cells to elevate cell counts.

Disease Research Area - Cardiovascular Disease, Oncology

Application Area - Cardiovascular, Intracellular Signaling, Oncology & Cancer

  • Recommended Components
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  • Kit Contents
  • References
  • Documentation
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5 plate size
50 plate size
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