R-PLEX Human RAGE (soluble) Antibody Set

R-PLEX Human RAGE (soluble) Antibody Set Overview
The R-PLEX Human RAGE (soluble) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of RAGE (soluble) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human RAGE (soluble) Antibody Set Features
  • Measures human RAGE (soluble) in plasma
  • Dynamic range: 4.5 - 25,000 pg/mL
  • Median LLOD: 4.5 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human RAGE (soluble) Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human RAGE (soluble) Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human RAGE (soluble) Antibody Set
RAGE (soluble) Analyte

Description - Soluble Receptor of Advanced Glycation End-products (RAGE [soluble], AGER, sRAGE, SCARJ1) is a member of the immunoglobulin superfamily of cell surface molecules. RAGE is a receptor for serum amyloid A, amyloid-beta protein, and members of the S100/calgranulin superfamily. RAGE mediates interactions of nonenzymatic glycosylated proteins that accumulate in vascular tissue. The soluble version results from secretion and from enzymatic cleavage of the extracellular domain of RAGE.

Disease Research Area - Autoimmune & Inflammation, Neurodegenerative, Vascular and Tissue Injury

Application Area - Immunology/Inflammation

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5 plate size
50 plate size
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