R-PLEX Human PYY (active) Antibody Set

R-PLEX Human PYY (active) Antibody Set Overview
The R-PLEX Human PYY (active) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PYY (active) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PYY (active) Antibody Set Features
  • Measures human PYY (active) in serum and plasma
  • Dynamic range: 146-20,000 pg/mL
  • Median LLOD: 146 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PYY (active) Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human PYY (active) Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human PYY Active Antibody Set
PYY (active) Analyte

Description - Peptide-YY (PYY, PYY1) is a peptide secreted from the intestinal L cells in proportion to the caloric content of a meal. Plasma PYY levels rise within 15 minutes and remain elevated for up to 6 hours. Two forms, PYY(1-36) and PYY(3-36), are released into circulation. DPP-IV converts PYY(1-36) to PYY(3-36). Both mediate satiety, decrease gastrointestinal motility, and increase water absorption. The capture antibody recognizes the amino acid 3 terminus; the assay recognizes PYY(3-36).

Disease Research Area - Metabolic Diseases

Application Area - Metabolic

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5 plate size
50 plate size
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