R-PLEX Human PP Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human PP Antibody Set Overview
The R-PLEX Human PP Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PP in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human PP Antibody Set Features
  • Measures human PP in serum and plasma
  • Dynamic range: 0.21 - 2,500 pg/mL
  • Median LLOD: 0.21 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human PP Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human PP Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human PP Antibody Set
PP Analyte

Description - Pancreatic Polypeptide (PP, pancreatic prohormone, PPY) is produced by PP cells, which populate the Islets of Langerhans, and to a lesser extent, the pancreatic duct. PP consists of 36 amino acids and is similar to NPY and PYY, having high affinity for the Y4 receptor. It must be amidated at the C-terminus to possess complete activity. PP is secreted from the pancreas after a meal. Its actions are varied and are influenced by feedback from the CNS. PP often functions as an antagonist to cholecystokinin.

Disease Research Area - Metabolic Diseases, Oncology

Application Area - Metabolic, Oncology & Cancer

Note: This antibody set also detects PP from non-human primate (NHP) samples.

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50 plate size
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