R-PLEX Human OX40L Antibody Set

R-PLEX Human OX40L Antibody Set Overview
The R-PLEX Human OX40L Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of OX40L in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human OX40L Antibody Set Features
  • Measures human OX40L in serum, plasma, and cell lysate
  • Dynamic range: 6.6-50,000 pg/mL
  • Median LLOD: 6.6 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human OX40L Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human OX40L Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human OX40L Antibody Set
OX40L Analyte

Description - OX40L (TNFSF4, CD252, gp34, OX40 ligand) is an immune checkpoint protein that is expressed by certain antigen-presenting cells. When OX40L binds to OX40 on cytotoxic T cells, it promotes replication and survival of those T cells. When OX40L binds to OX40 on regulatory T cells, their supression of cytotoxic T cells is muted resulting in enhanced T-cell activation. OX40L is also known to suppress apoptosis and is involved in T cell-dependent B-cell proliferation and differentiation.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunology/Inflammation, Immuno-Oncology

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5 plate size
50 plate size
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