R-PLEX Human MMP-9 Antibody Set

R-PLEX Human MMP-9 Antibody Set Overview
The R-PLEX Human MMP-9 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MMP-9 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human MMP-9 Antibody Set Features
  • Measures human MMP-9 in serum, plasma, and urine
  • Dynamic range: 27 - 500,000 pg/mL
  • Median LLOD: 27 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human MMP-9 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human MMP-9 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human MMP-9 Antibody Set
MMP-9 Analyte

Description - Matrix metalloprotease-9 (MMP9, MMP-9, GELB, CLG4B, MANDP2) is a member of the matrix metalloproteinase family of endopeptidases which are critically important in extracellular matrix remodeling. MMP-9 is a glycoprotein that plays a significant role in tissue remodeling, morphogenesis and cytokine activation. It degrades interstitial collagens, proteoglycan core protein, elastin and type IV collagen in the basement membrane. MMP-9 can also cleave several non-matrix molecules such as IL-1b, IL-8, platelet factor-4, GRO-a, and amyloid b peptide. It is thought that MMP-9 plays an important role in various disease processes, including cancer, rheumatoid arthritis and atherosclerosis.

Disease Research Area - Cancer, Rheumatoid Arthritis, Atherosclerosis

Application Area - Angiogenesis & Vascular, Oncology & Cancer, Cardiovascular

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5 plate size
50 plate size
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