R-PLEX Human MMP-3 Antibody Set

R-PLEX Human MMP-3 Antibody Set Overview
The R-PLEX Human MMP-3 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MMP-3 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human MMP-3 Antibody Set Features
  • Measures human MMP-3 in serum, plasma, and urine
  • Dynamic range: 5.5 - 100,000 pg/mL
  • Median LLOD: 5.5 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human MMP-3 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human MMP-3 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human MMP-3 Antibody Set
MMP-3 Analyte

Description - Matrix metalloprotease-3 (MMP3, SL-1, STMY, STR1, CHDS6, MMP-3, STMY1, stromelysin-1) is a member of the matrix metalloproteinase family of endopeptidases which are critically important in extracellular matrix remodeling. MMP-3 plays an important role in the degradation and reconstitution of extracellular matrix. It is produced as an inactive preform and is proteolytically cleaved to its active form. An important function of MMP-3 is to activate other latent-type MMPs. Recent studies have implicated MMP-3 in the pathogenesis of Alzheimer’s disease. MMP-3 has also been associated with conditions such as rheumatoid arthritis.

Disease Research Area - Alzheimer's Disease, Rheumatoid Arthritis, Cancer

Application Area - Angiogenesis & Vascular, Oncology & Cancer, Cardiovascular

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5 plate size
50 plate size
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