R-PLEX Human MMP-1 Antibody Set

R-PLEX Human MMP-1 Antibody Set Overview
The R-PLEX Human MMP-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MMP-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human MMP-1 Antibody Set Features
  • Measures human MMP-1 in serum, plasma, and urine
  • Dynamic range: 1.9 - 10,000 pg/mL
  • Median LLOD: 1.9 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human MMP-1 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human MMP-1 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human MMP-1 Antibody Set
MMP-1 Analyte

Description - Matrix metalloproteinase-1 (MMP1, CLG, CLGN, interstitial collagenase) is a member of a family of endopeptidases which are critically important in extracellular matrix remodeling. MMP-1 cleaves collagens of types I, II, III, VII and X. MMP-1 is thought to play an important role in the pathogenesis of rheumatoid arthritis and osteoarthritis by mediating cartilage and bone destruction. MMP-1 has been found to be up-regulated in a variety of cancers and has been suggested to be associated with tumor invasion and metastasis. In addition to collagen, MMP-1 also cleaves a number of non-matrix substrates and probably plays a role in the regulation of cellular behavior.

Disease Research Area - Cancer, Rheumatoid Arthritis, Osteoarthritis

Application Area - Inflammation, Oncology & Cancer

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5 plate size
50 plate size
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