R-PLEX Human ICAM-3 Antibody Set

R-PLEX Human ICAM-3 Antibody Set Overview
The R-PLEX Human ICAM-3 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of ICAM-3 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human ICAM-3 Antibody Set Features
  • Measures human ICAM-3 in serum, plasma, and urine
  • Dynamic range: 7.2 - 200,000 pg/mL
  • Median LLOD: 7.2 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human ICAM-3 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human ICAM-3 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human ICAM-3 Antibody Set
ICAM-3 Analyte

Description - ICAM-3 (CD50, CDW50, ICAM-R, ICAM3, intercellular adhesion molecule 3) is a member of the intercellular adhesion molecule (ICAM) family and is a transmembrane glycoprotein that is constitutively expressed in leukocytes. The mature ICAM-3 protein acts as both a cellular adhesion molecule and a signalling molecule. ICAM-3 binds to leukocyte adhesion LFA-1 protein (CD11a/CD18) and facilitates cell-cell interactions that take place in the immune system. This assay detects the soluble form of ICAM-3.

Disease Research Area - Chronic Obstructive Pulmonary Disease, Osteoarthritis, Autoimmune Disorders

Application Area - Adhesion, Immunology

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5 plate size
50 plate size
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