R-PLEX Human gp130 (soluble) Antibody Set

R-PLEX Human gp130 (soluble) Antibody Set Overview
The R-PLEX Human gp130 (soluble) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of gp130 (soluble) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human gp130 Features
  • Measures human gp130 (soluble) in Serum
  • Dynamic range: 32 - 375,000 pg/mL
  • Median LLOD: 32 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human gp130 was assessed and representative data is presented below.

Figure 1. R-PLEX Human gp130 Calibration Curve
Calibration curve for R-PLEX Human gp130
gp130 (soluble) Analyte

Description - Soluble glycoprotein 130 (GP130, gp130, CD130, CDw130, IL-6RB, IL6ST) is a vital protein that supports transmembrane signaling of IL-6, IL-11, IL-27, CT-1, CNTF, LIF, and OSM. It is present on most cell types, depending on their activation state. Soluble gp130 may be produced by cleavage of the extracellular domain or by splice variants, and acts as an inhibitor of classic IL-6 activity.

Application Area - Cardiovascular Disease, Autoimmune and Inflammation, Metabolic Disease

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5 plate size
50 plate size
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