R-PLEX Human GIP Active Antibody Set

R-PLEX Human GIP Active Antibody Set Overview
The R-PLEX Human GIP (active) Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of GIP (active) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human GIP (active) Antibody Set Features
  • Measures human GIP (active) in serum and plasma
  • Dynamic range: 1.9-7,500 pg/mL
  • Median LLOD: 1.9 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human GIP (active) Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human GIP (active) Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human GIP Active Antibody Set
GIP (active) Analyte

Description - Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide, incretin) is a glucose-dependent, insulinotropic peptide. GIP is synthesized by enteroendocrine K cells in the duodenal and jejunal mucosa and is secreted into plasma in response to nutrient flow through the small intestine. GIP protects the small intestine from acid damage. Applications that exploit GIP activity to regulate glucose homeostasis are under investigation. GIP (active) is the 1-42 protein.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic

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