R-PLEX Human FAP-α/SEPR Antibody Set Overview
The R-PLEX Human FAP-α/SEPR Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FAP-α/SEPR in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human FAP-α/SEPR Antibody Set Features
- Measures human FAP-α/SEPR in plasma
- Dynamic range: 1.0 - 10,000 pg/mL
- Median LLOD: 1.0 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human FAP-α/SEPR Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human FAP-α/SEPR Antibody Set Calibration Curve
FAP-α/SEPR Analyte
Description - Fibroblast Activation Protein-α (FAP-α, FAPA, SIMP, DPPIV, FAPalpha, seprase, FAP) is a member of the serine protease family and is a type 2 membrane-bound glycoprotein. It has similar activity as DPPIV peptidase and collagenases, and is expressed by stromal fibroblasts. FAP-α has been associated with enhancing tumor activity in cell lines, with elevated levels being indicative of poor prognosis. Sites of tissue remodeling generally have high FAP-α.
Disease Research Area - Cancer
Application Area - Angiogenesis & Vascular, Apoptosis, Cell Adhesion
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Recommended Components
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Specifications
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Kit Contents
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Documentation
You will need plates, diluents, and read buffer to run your assay. Please select from the below menu.
R-PLEX Sets are intended to be used with other MSD components such as plates, diluents and MSD Read Buffer. If you don’t already have these items, you can purchase them along with your Antibody Set(s). The “Recommended Components” tab provides helpful suggestions or you can call MSD Customer Service (Phone number) for assistance. R-PLEX Sets can also be used with other antibody sets such as U-PLEX antibody sets (make a link to UPLEX landing page) for multiplex measurements.
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Cardiovascular
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Analyte(s)
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FAP-α/SEPR
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Sheep Polyclonal
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Dynamic Range
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1.0 - 10,000 pg/mL
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Sample Type
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Plasma
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Recombinant standards
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Recombinant protein expressed in Sf21 insect cells
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LLOD (Sensitivity)
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1.0 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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2191
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UniProt ID(s)
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Q12884
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Assay Diluent(s)
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Diluent 101
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Antibody Diluent(s)
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Diluent 37
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Product Description
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Storage
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Quantity per Kit
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Human FAP-α/SEPR Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human FAP-α/SEPR Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human FAP-α/SEPR Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human FAP-α/SEPR Calibrator
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≤-70°C
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50 vial
(1 vial)
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Product Inserts
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Product Highlights
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters