R-PLEX Human FAP-α/SEPR Antibody Set Overview
The R-PLEX Human FAP-α/SEPR Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FAP-α/SEPR in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
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R-PLEX Human FAP-α/SEPR Antibody Set Features
- Measures human FAP-α/SEPR in plasma
- Dynamic range: 1.0 - 10,000 pg/mL
- Median LLOD: 1.0 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human FAP-α/SEPR Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human FAP-α/SEPR Antibody Set Calibration Curve
FAP-α/SEPR Analyte
Description - Fibroblast Activation Protein-α (FAP-α, FAPA, SIMP, DPPIV, FAPalpha, seprase, FAP) is a member of the serine protease family and is a type 2 membrane-bound glycoprotein. It has similar activity as DPPIV peptidase and collagenases, and is expressed by stromal fibroblasts. FAP-α has been associated with enhancing tumor activity in cell lines, with elevated levels being indicative of poor prognosis. Sites of tissue remodeling generally have high FAP-α.
Disease Research Area - Cancer
Application Area - Angiogenesis & Vascular, Apoptosis, Cell Adhesion
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Recommended Components
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Specifications
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Kit Contents
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Documentation
Why do I need other components
Catalog No.
Product Name
Size
R50AA-4
R92TG-3
L45SA-1
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Application(s)
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Cardiovascular
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Analyte(s)
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FAP-α/SEPR
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Species
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Human
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Sheep Polyclonal
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Dynamic Range
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1.0 - 10,000 pg/mL
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Sample Type
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Plasma
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Recombinant standards
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Recombinant protein expressed in Sf21 insect cells
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LLOD (Sensitivity)
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1.0 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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2191
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UniProt ID(s)
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Q12884
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Assay Diluent(s)
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Diluent 101
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Antibody Diluent(s)
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Diluent 37
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Product Description
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Storage
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Quantity per Kit
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Human FAP-α/SEPR Antibody Set (5 Plate Size)
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2-8°C
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1 ea
(5 plate size)
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Human FAP-α/SEPR Calibrator
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≤-70°C
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5 vial
(1 vial)
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Product Description
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Storage
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Quantity per Kit
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Human FAP-α/SEPR Antibody Set (5 Plate Size)
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2-8°C
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10 ea
(5 plate size)
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Human FAP-α/SEPR Calibrator
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≤-70°C
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50 vial
(1 vial)
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Product Inserts
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Product Highlights
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SDS
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Handouts
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Datasheets
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
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