R-PLEX Human FAP-α/SEPR Antibody Set

R-PLEX Human FAP-α/SEPR Antibody Set Overview
The R-PLEX Human FAP-α/SEPR Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FAP-α/SEPR in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human FAP-α/SEPR Antibody Set Features
  • Measures human FAP-α/SEPR in plasma
  • Dynamic range: 1.0 - 10,000 pg/mL
  • Median LLOD: 1.0 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human FAP-α/SEPR Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human FAP-α/SEPR Antibody Set Calibration Curve
Calibration curve for R-PLEX Human FAP-α/SEPR Antibody Set
FAP-α/SEPR Analyte

Description - Fibroblast Activation Protein-α (FAP-α, FAPA, SIMP, DPPIV, FAPalpha, seprase, FAP) is a member of the serine protease family and is a type 2 membrane-bound glycoprotein. It has similar activity as DPPIV peptidase and collagenases, and is expressed by stromal fibroblasts. FAP-α has been associated with enhancing tumor activity in cell lines, with elevated levels being indicative of poor prognosis. Sites of tissue remodeling generally have high FAP-α.

Disease Research Area - Cancer

Application Area - Angiogenesis & Vascular, Apoptosis, Cell Adhesion

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Order Details
Catalog No
Size
Price in USD
Qty
F21YI-3
5 plate size
$550.00
F21YI-8
50 plate size
$4,950.00
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