R-PLEX Human FAP-α/SEPR Antibody Set Overview
The R-PLEX Human FAP-α/SEPR Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FAP-α/SEPR in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products
click here.
R-PLEX Human FAP-α/SEPR Antibody Set Features
- Measures human FAP-α/SEPR in plasma
- Dynamic range: 1.0 - 10,000 pg/mL
- Median LLOD: 1.0 pg/mL
- Can be used to develop individual analyte assays as well as multiplex panels
Typical Data
Calibration curve for the R-PLEX Human FAP-α/SEPR Antibody Set was assessed and representative data is presented below.
Figure 1. R-PLEX Human FAP-α/SEPR Antibody Set Calibration Curve
FAP-α/SEPR Analyte
Description - Fibroblast Activation Protein-α (FAP-α, FAPA, SIMP, DPPIV, FAPalpha, seprase, FAP) is a member of the serine protease family and is a type 2 membrane-bound glycoprotein. It has similar activity as DPPIV peptidase and collagenases, and is expressed by stromal fibroblasts. FAP-α has been associated with enhancing tumor activity in cell lines, with elevated levels being indicative of poor prognosis. Sites of tissue remodeling generally have high FAP-α.
Disease Research Area - Cancer
Application Area - Angiogenesis & Vascular, Apoptosis, Cell Adhesion
-
Recommended Components
-
Specifications
-
Kit Contents
-
-
Resources
You will need plates, diluents, and read buffer to run your assay.
Please select from the below menu.
Catalog No.
Product Name
Size
L45SA-1
R50AA-4
R92TG-3
|
Application(s)
|
|
Cardiovascular
|
|
Analyte(s)
|
|
FAP-α/SEPR
|
|
Species
|
|
Human
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
Detection Antibody
|
|
Sheep Polyclonal
|
|
Dynamic Range
|
|
1.0 - 10,000 pg/mL
|
|
Sample Type
|
|
Plasma
|
|
Recombinant standards
|
|
Recombinant protein expressed in Sf21 insect cells
|
|
LLOD (Sensitivity)
|
|
1.0 pg/mL
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Statement
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
Storage Condition
|
|
Multi-Component
|
|
Gene ID
|
|
2191
|
|
UniProt ID
|
|
Q12884
|
|
Assay Diluent(s)
|
|
Diluent 101
|
|
Antibody Diluent(s)
|
|
Diluent 37
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Human FAP-α/SEPR Antibody Set (5 Plate Size)
|
2-8°C | 1 ea
(5 plate size) |
|
Human FAP-α/SEPR Calibrator
|
≤-70°C | 5 vial
(1 vial) |
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Human FAP-α/SEPR Antibody Set (5 Plate Size)
|
2-8°C | 10 ea
(5 plate size) |
|
Human FAP-α/SEPR Calibrator
|
≤-70°C | 50 vial
(1 vial) |
|
Product Inserts
|
|
|
|
Product Highlights
|
|
|
|
SDS
|
|
|
|
Handouts
|
|
|
|
Datasheets
|
|
|
Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters