R-PLEX Human CD31 Antibody Set

R-PLEX Human CD31 Antibody Set Overview
The R-PLEX Human CD31 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of PECAM-1/CD31 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human CD31 Antibody Set Features
  • Measures human PECAM-1/CD31 in serum and plasma
  • Dynamic range: 29 - 10,000 pg/mL
  • Median LLOD: 29 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human CD31 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human CD31 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human CD31 Antibody Set
PECAM-1/CD31 Analyte

Description - Platelet endothelial cell adhesion molecule / Cluster of differentiation 31 (CD31, PECAM-1, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM) is a 130 kDa transmembrane protein (type I) found on the surface of endothelial cell as well as several types of blood cells including monocytes, neutrophils, platelets, and certain T-cells. PECAM-1 belongs to the Cell Adhesion Molecule (CAM) immunoglobulin superfamily and is believed to be involved in leucocyte migration through intercellular junctions. Like many of the proteins in this family, PECAM-1 may also be involved in angiogenesis and activation of the integrin pathway.

Disease Research Area - Angiogenesis

Application Area - Angiogenesis & Vascular, Cell Adhesion

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5 plate size
50 plate size
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