R-PLEX Human BDNF Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human BDNF Antibody Set Overview
The R-PLEX Human BDNF Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of BDNF in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human BDNF Antibody Set Features
  • Measures human BDNF in Serum, Plasma, CSF
  • Dynamic range: 16 - 50,000 pg/mL
  • Median LLOD: 16 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human BDNF Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human BDNF Antibody Set Calibration Curve
Calibration curve for R-PLEX Human BDNF Antibody Set
BDNF Analyte

Description - Brain-Derived Neurotrophic Factor (BDNF, ANON2, BULN2) is part of the nerve growth factor family. BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. The protein is active in the hippocampus, cortex, and basal forebrain, and is important for long-term memory. BDNF is neuroprotective in neurodegenerative conditions, peripheral nerve injury, and stroke. BDNF has been associated with brain trauma and neurodegenerative conditions.

Application Area - Neurodegenerative

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