Click image to enlarge
This kit provides assay-specific components for the quantitative determination of phosphorlated BCL2-antagonist of cell death (phospho-BAD) (Ser112) in human and non-human primate whole cell lysates. Phosphorylation of BAD by kinases such as Akt, PKA, and p90RSK blocks its pro-death activity. phospho-BAD binds to the 14-3-3 protein and displaces its binding to Bcl-2 and Bcl-xL.
-
-
Specifications
-
-
Documentation
-
References
|
Application(s)
|
|
Phosphoproteins
,
Intracellular Signaling
|
|
|
Analyte(s)
|
|
BAD
|
|
|
Species
|
|
Human, Non-human primate
|
|
|
Plate Type
|
|
96-well
|
|
|
Instrument(s)
|
|
MESO SECTOR S 600MM
,
MESO QuickPlex SQ 120MM
,
MESO SECTOR S 600
,
MESO QuickPlex SQ 120
,
SECTOR Imager 6000
,
SECTOR Imager 2400
|
|
|
Capture Antibody
|
|
Mouse Monoclonal
|
|
|
Detection Antibody
|
|
Rabbit Polyclonal
|
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
|
Kit Model
|
|
Whole Cell Lysate
|
|
|
Storage Statement(s)
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
|
Storage Condition
|
|
2-8 °C
|
|
|
Product Inserts
|
|
|
|
Datasheets
|
|
|
|
SDS
|
|
|
|
Title
|
Journal
|
Year
|
|
Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233.
|
|
|
|
A novel peptide, colivelin, prevents alcohol-induced apoptosis in fetal brain of C57BL/6 mice: Signaling pathway investigations.
|
|
|
|
Multiplexing siRNAs to compress RNAi-based screen size in human cells.
|
|
|
|
|
|
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters