Mouse IL-17F Antibody

The Mouse IL-17F Antibody is a SULFO-TAG conjugated detection antibody for IL-17F. It is the same detection antibody that is in the V-PLEX Mouse IL-17F Assay. Detection antibody is supplied as a 50X concentrated solution. Mouse IL-17F is a cross-linked homodimer, a prototypical biomarker for Th17 cells, and is closely related to IL-17A. IL-17A can pair with IL-17F to form the IL-17A/F heterodimer of intermediate activity. IL-17F has greater affinity for IL-17RC receptor while IL-17A prefers IL-17RA, so some target-based differentiation is obtained when more than 1 of the possible 3 dimers is present. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL-2, TGF-β, and MCP-1.

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