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The Mouse IL-17 Ultra-Sensitive Kit provides assay-specific components for the quantitative determination of endogenous IL-17 in mouse serum and plasma.
Mouse IL-17A, also known as CTLA-8, is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It is a member of a six-species family of proteins (IL-17A-F) and is expressed by the TH17 cell lineage. This lineage selectively produces proinflammatory cytokines including IL-17A, IL-17F, IL-21, and IL-22. IL-17A can dimerize with IL-17F. The receptor for IL-17A, IL-17F, and the IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC. Elevated levels of IL-17A have been associated with several conditions including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis.
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Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection
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Reliability of self-sampling for accurate assessment of respiratory virus viral and immunologic kinetics
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Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity
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Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial
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Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy.
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