Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the
U-PLEX Mouse MIP-3α Assay.
V-PLEX Plus Mouse MIP-3α Kit Overview The V-PLEX Plus Mouse MIP-3α Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse MIP-3α Kit enables the sensitive detection of native MIP-3α in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays
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The V-PLEX Mouse MIP-3α assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.
V-PLEX Mouse MIP-3α Assay Features - Validated to measure mouse MIP-3α in serum, plasma, cell culture supernatants, PBMCs, and urine
- Dynamic range: 0.389 – 530 pg/mL
- LLOQ: 3.42 pg/mL
Typical Data Calibration curve for the V-PLEX Plus Mouse MIP-3α Kit was assessed and representative data is presented below.
Figure 1. V-PLEX Plus Mouse MIP-3α Kit Calibration Curve MIP-3α Analyte
Description - Mouse macrophage inflammatory protein 3α (CCL20, SCYA20, LARC, CKb4; Gene ID: 20297) is a chemokine with inflammatory and homeostatic functions. Initially identified in the liver, MIP-3α is expressed in lymphatic tissue, lung tissue, macrophages, dendritic cells, B- and T- lymphocytes, and eosinophilic granulocytes as well as in normal colon, pancreas, prostate, uterine cervix, and skin. MIP-3α is a ligand for the CCR6 receptor; it is also chemotactic for CCR6+ cells such as dendritic cells and Th17 T cells.
Disease Research Area - Autoimmune & Inflammation, Cardiovascular Disease, Metabolic Diseases, Oncology, Vascular and Tissue Injury
Application Area - Cytokines & Chemokines, Inflammatory Injury