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The Liver Injury Panel 1 (rat) Kit provides the assay-specific components for the quantitative determination of arginase-1 and alpha glutathione S-transferase (αGST) in rat serum and plasma.
Arginase-1, also known as Liver Type Arginase, is the final enzyme of the urea cycle. It is a ubiquitous cytosolic enzyme expressed at high levels in the liver of ureotelic animals and plays a key role in the disposal of excess nitrogen from amino acid and nucleotide metabolism. αGST is a detoxification enzyme that catalyzes the conjugation of toxins to GST. Arginase-1 and αGST offer an advantage in drug safety testing since they are found in the serum and plasma of both rats and humans; suggesting that they can be used to bridge pre-clinical and clinical studies.
Please note: MSD has transitioned this product to a status of “made-to-order” with a minimum order size of 25 plates. For an order of the 5-plate pack size, the minimum quantity is 5 packs (25 plates). The 1-plate and 25-plate pack sizes have been discontinued.
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Specifications
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Documentation
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Application(s)
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Toxicology
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Liver Injury
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Analyte(s)
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α-GST, Arginase-1
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Species
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Rat
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Instrument(s)
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SECTOR Imager 2400
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MESO SECTOR S 600MM
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SECTOR Imager 6000
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MESO QuickPlex SQ 120MM
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MESO QuickPlex SQ 120
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MESO SECTOR S 600
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Plate Type
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96-well
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Inserts
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Datasheets
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Certificate of analysis
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SDS
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Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters