V-PLEX Th17 Assays

V-PLEX: NEW Th17 Cytokine Assays - Reproducible and Validated - Available Now

 

V-PLEX: MSD’s Validated Assay Platform

V-PLEX validated assays deliver reproducibility and reliability to support the most demanding long-term studies. V-PLEX assays maximize consistency in results and confidence in data.

Learn more about V-PLEX Assays


Th17: A Pathway Implicated in Immune Disorders

Th17 cells play key roles in immune responses. Improper regulation of their proinflammatory activities contributes to numerous pathogenic conditions such as type 1 diabetes, Crohn’s disease, lupus, multiple sclerosis, and rheumatoid arthritis.

Accelerate your Th17-pathway research with the quality and performance you expect from MSD.



V-PLEX analytes are available as validated individual assays or as part of a validated multiplex panel.

Analytes   Human Mouse NHP Rat
IFN-γ  
IL-1β  
IL-2    
IL-4    
IL-5  
IL-6  
IL-8      
IL-10  
IL-12p70      
IL-13      
IL-16
NEW
   
IL-17A
NEW
 
IL-17C
NEW
   
IL-17E/IL-25
NEW
     
IL-17F
NEW
     
IL-21
NEW
   
IL-22
NEW
   
IL-23
NEW
   
IL-27
NEW
     
IL-31
NEW
   
KC/GRO      
MIP-3α
NEW
   
TNF-α    

For greater convenience, select a pre-configured V-PLEX Plus* product, available in 1, 5, and 25-plate pack sizes.

Selected Panels of Interest   Catalog Number Analytes
V-PLEX Plus TH17
Panel 1 (human)
NEW
K15085G IL‑17A, IL‑21, IL‑22, IL‑23, IL‑27, IL‑31, MIP‑3α
V-PLEX Plus Proinflammatory
Panel 1 (human)
  K15049G IFN‑γ, IL‑1β, IL‑2, IL‑4, IL‑6, IL‑8, IL‑10, IL‑12p70, IL‑13, TNF‑α
V-PLEX Plus Cytokine
36-Plex Kit (human)
NEW
K15089G Eotaxin, Eotaxin‑3, GM‑CSF, IFN‑γ, IL‑1α, IL‑1β, IL‑2, IL‑4, IL‑5, IL‑6, IL‑7, IL‑8, IL‑8 (HA**), IL‑10, IL‑12p70, IL‑12/IL‑23p40, IL‑13, IL‑15, IL‑16, IL‑17A, IL‑21, IL‑22, IL‑23, IL‑27, IL‑31, IP‑10, MCP‑1, MCP‑4, MDC, MIP‑1α, MIP‑1β, MIP‑3α, TARC, TNF‑α, TNF‑β, VEGF‑A
V-PLEX Plus Cytokine
46-Plex Kit (human)
NEW
K15088G CRP, Eotaxin, Eotaxin‑3, FGF (basic), Flt‑1/VEGFR‑1, GM‑CSF, ICAM‑1, IFN‑γ, IL‑10, IL‑12/IL‑23p40, IL‑12p70, IL‑13, IL‑15, IL‑16, IL‑17A, IL‑1α, IL‑1β, IL‑2, IL‑21, IL‑22, IL‑23, IL‑27, IL‑31, IL‑4, IL‑5, IL‑6, IL‑7, IL‑8, IL‑8 (HA**), IP‑10, MCP‑1, MCP‑4, MDC, MIP‑1α, MIP‑1β, MIP‑3α, PlGF, SAA, TARC, Tie‑2, TNF‑α, TNF‑β, VCAM‑1, VEGF‑A, VEGF‑C, VEGF‑D
V-PLEX Plus TH17 Panel 1 (mouse)
NEW
K15246G IL‑16, IL‑17A, IL‑17C, IL‑17E/IL‑25, IL‑17F, IL‑21, IL‑22, IL‑23, IL‑31, MIP‑3α
V-PLEX Plus Mouse Cytokine 29-Plex Kit
NEW
K15267G IFN‑γ, IL‑1β, IL‑2, IL‑4, IL‑5, IL‑6, IL‑9, IL‑10, IL‑12p70, IL‑15,  IL‑16, IL‑17A, IL‑17 A/F, IL‑17C, IL‑17E/IL‑25, IL‑17F, IL‑21, IL‑22, IL‑23, IL‑27p28/IL‑30, IL‑31, IL‑33, IP‑10, KC/GRO, MCP‑1, MIP‑1α, MIP‑2, MIP‑3α, TNF‑α
* V-PLEX Plus Panels include controls, wash buffer, and plate seals.
Standard versions are also available.
** High Abundance
Customize a V-PLEX Panel


V-PLEX TH17 Figure 1

Figure 1. Typical calibration curves for the TH17
Panel 1 (human) assay.

V-PLEX Kit
Assay IL-17A (Gen. B) IL-21 IL-22 IL-23 IL-27 IL-31 MIP-3α
Dynamic range, pg/mL 5.86 - 1,950 1.65 - 650 2.78 - 325 4.60 - 3,250 38.7 - 13,000 4.22 - 650 0.588 - 325


Additional Options

If you need the flexibility to configure custom multiplexes in your own lab, please explore our U-PLEX options for Th17 pathway research.