Uromodulin

Uromodulin (UMOD, Tamm-Horsfall glycoprotein, THP, HNFJ, THGP) is a glycoprotein that is produced in the thick ascending limb of the loop of Henle. It is the most abundant protein in normal, healthy urine. Increased expression of UMOD can cause it to leak into the renal interstitium resulting in the recruitment and stimulation of an immune response, causing inflammation and kidney damage. UMOD deposits have been observed in renal biopsies of tubulointerstitial disease. Uromodulin along with uropontin and nephrocalcin are the primary components of kidney stones.

 

Uromodulin Singleplex Products

Our Uromodulin immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Uromodulin. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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Uromodulin Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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