PD1

Programmed cell death 1 (PD1, CD279, SLEB2, PD-1) is an immune checkpoint receptor that is important in regulating the immune system and its recognition of self. PD-1 is a member of the immunoglobulin superfamily and is expressed by both T cells and B cells. Two ligands recognize this receptor, PD-L1 and PD-L2. Binding of either ligand acts to inhibit the immune system response, which reduces autoimmune activity as well as anti-cancer activity. Conversely, inhibitors of this ligand-receptor interaction enhance cancer recognition and fighting activity.

 

PD1 Singleplex Products

Our PD1 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of PD1. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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