MMP-2

Matrix metalloproteinase (MMP) are a family of endopeptidases which are critically important in extracellular matrix remodeling. They are highly homologous to each other and belong to a larger family of proteases known as the metzincin superfamily. MMP-2 degrades type IV collagen, which is the major component of basement membranes. MMP-2 is expressed in fibroblasts during development and tissue regeneration. MMP-2 is tightly regulated at the transcriptional and post-transcriptional levels. MMP-2 in coordination with other MMPs, play a role in normal tissue remodeling events such as embryonic development, angiogenesis, ovulation, mammary gland involution and wound healing. MMP-2 has also been associated with the ability of tumors to invade and become neovascularized, and is one of the important targets for the development of antitumor therapeutics.

 

MMP-2 Singleplex Products

Our MMP-2 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of MMP-2. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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MMP-2 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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