LAG3

Lymphocyte-activation gene 3 (LAG3, CD223, LAG-3, FDC) encodes the LAG3 protein that is a member of the immunoglobulin superfamily. It is expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic cells, and binds with high affinity to MHC class 2 molecules. LAG3 is an immune checkpoint receptor that is of interest in immunotherapy. LAG3 antagonists activate T effector cells and inhibit regulatory T-cell suppression, and may have roles in autoimmune disorders.

 

LAG3 Singleplex Products

Our LAG3 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of LAG3. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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