IL-2Rα

Interleukin 2 receptor alpha (CD25, IDDM10, IMD41, p55) is one of three proteins that make up the IL-2 receptor, along with IL-2Rβ and IL-2Rγ. The receptor can assemble in different combinations into receptors with varied affinities for IL-2. The alpha subunit does not contribute to the intracellular signaling when IL-2 binds to the receptor; instead, it is recycled to the surface after activation and internalization, while the other subunits are degraded. Levels of free soluble forms of IL-2Rα rise along with increased surface expression when immune cells are activated. The function of soluble IL-2Rα is unclear. IL-2Rα is a biomarker for immune system function, Chagas disease, and allograft rejection.

Application Areas

IL-2Rα assays are available for human and NHP samples in both single and multiplex formats.
Select these or create a custom multiplex assay including IL-2Rα with the U-PLEX Assay Designer.

 

IL-2Rα Singleplex Products

Our IL-2Rα immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of IL-2Rα. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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IL-2Rα Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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