Granzyme A

Granzyme A (GZMA, CTLA3, CTL tryptase) is a protease found in abundant quantities in secretory granules of cytotoxic T cells and NK cells. When secreted into the target cell via the immunological synapse, Granzyme A causes cell death by cleaving various proteins including those in the mitochondria and in the nucleosome that then degrade the DNA.This protease has been found to be elevated in patients who currently have an infectious disease or are in a pro-inflammatory state.

 

Granzyme A Singleplex Products

Our Granzyme A immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Granzyme A. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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