Growth Differentiation Factor 15 (GDF-15, PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF15) is a member of the TGF-β superfamily and is expressed in a broad range of cell types. GDF-15 acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. GDF-15 is released at sites of inflammation and regulates macrophage activation. GDF-15 expression in liver can be up-regulated during the injury of organs such as liver, kidney, heart and lung.


GDF-15 Singleplex Products

Our GDF-15 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of GDF-15. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.


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