EGF

Epidermal Growth Factor (EGF, HOMG4, URG, Urogastrone) is the central member of related proteins in the EGF-like family. It plays an important role in cell regulation, proliferation, and survival. EGF binds to its cognate receptor EGFR, also known as ErbB1. ErbB2, ErbB3, and ErbB4 bind other members of the EGF family of ligands and then undergo homo- or hetero-dimerization. These dimers autophosphorylate and initiate signal transduction cascades. EGF is a biomarker of tubulointerstitial damage in human obstructive nephropathy. The level of EGF increases in ischemic acute renal failure. EGF is therefore a potentially useful tool in kidney disease research.

 

EGF Singleplex Products

Our EGF immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of EGF. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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EGF Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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