CTACK

Cutaneous T-cell attracting chemokine (CTACK/CCL27) is a small chemotactic cytokine belonging to the CC family of chemokines which has well-appreciated roles in adhesion and directional homing of immune and inflammatory cells. It is pivotal in mediating the migration of lymphocytes into the skin by binding to the chemokine receptor CCR10. CTACK is predominantly and continuously expressed in the skin by keratinocytes and is highly upregulated in wounds and in inflammatory diseases like atopic dermatitis and psoriasis. Studies have shown that CTACK-CCR10 interaction directly regulates T-cell recruitment to inflamed skin and is the likely key regulator of basal T-cell trafficking during immunosurveillance.

 

CTACK Singleplex Products

Our CTACK immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of CTACK. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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CTACK Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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