Rat interleukin-13 (IL-13) is a 14.1 kDa glycosylated immunoregulatory cytokine with two intra-molecular disulfide bonds forming a bundled four α-helix configuration. It is secreted by a variety of immune cells. IL-13 is involved in a number of biological processes, including positive regulation of B-cell proliferation, macrophage activation, immunoglobulin production, protein secretion, and phosphorylation of Stat6 protein. IL-13 initially interacts with IL-13 Rα1 to form a low-affinity complex. The formation of this complex triggers association with IL-4 Rα to form a high-affinity complex that also functions as the type 2 IL-4 receptor complex. IL-13 also binds with high affinity to IL-13 Rα2, which is expressed intracellularly as a soluble protein as well as on the cell surface. It is involved in a number of disorders including allergic rhinitis, inflammatory bowel disease, and colorectal cancer. The Rat IL-13 Kit provides assay-specific components for the quantitative determination of endogenous IL-13 in rat urine, serum, plasma, and cell culture supernatants.
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Specifications
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Kit Contents
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References
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Documentation
Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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IL-13
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Species
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Rat
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Instrument
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MESO QuickPlex SQ 120
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SECTOR Imager 2400
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SECTOR Imager 6000
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MESO SECTOR S 600
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Goat Polyclonal
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LLOD (Sensitivity)
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1.97 pg/mL
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Dynamic Range
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1.97–1072pg/mL
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Sample Type
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Serum, Plasma, Urine, Cell Culture Supernatant
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Recombinant standards
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Expressed in E. coli
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Product Description
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Storage
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Quantity per Kit
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Proinflammatory Panel 1 (rat) Control 1
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2-8°C
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1 vial
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Proinflammatory Panel 1 (rat) Control 2
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2-8°C
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1 vial
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Proinflammatory Panel 1 (rat) Control 3
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2-8°C
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1 vial
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2-8°C
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1 vial (1 vial)
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2-8°C
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1 vial (75 μL)
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Proinflammatory Panel 2 (rat) Plate
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2-8°C
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1 each (1 each)
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Diluent Assembly 7 (includes Diluent 40 – 5 mL, Diluent 42 – 10 mL)
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≤-10°C
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1 each
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RT
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1 each (100 mL)
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RT
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1 each (50 mL)
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Blocker H, 20 mL
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RT
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1 bottle (20 mL)
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Product Description
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Storage
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Quantity per Kit
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Proinflammatory Panel 1 (rat) Control 1
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2-8°C
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5 vial
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Proinflammatory Panel 1 (rat) Control 2
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2-8°C
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5 vial
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Proinflammatory Panel 1 (rat) Control 3
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2-8°C
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5 vial
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2-8°C
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5 vial (1 vial)
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2-8°C
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1 vial (375 μL)
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Proinflammatory Panel 2 (rat) Plate
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2-8°C
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5 each (1 each)
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Diluent Assembly 8 (includes Diluent 40 – 25 mL, Diluent 42 – 50 mL)
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≤-10°C
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1 each
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RT
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1 each (100 mL)
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RT
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1 each (50 mL)
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Blocker H, 100 mL
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RT
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1 bottle (100 mL)
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Product Description
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Storage
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Quantity per Kit
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Proinflammatory Panel 1 (rat) Control 1
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2-8°C
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25 vial
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Proinflammatory Panel 1 (rat) Control 2
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2-8°C
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25 vial
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Proinflammatory Panel 1 (rat) Control 3
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2-8°C
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25 vial
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2-8°C
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25 vial (1 vial)
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2-8°C
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5 vial (375 μL)
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Proinflammatory Panel 2 (rat) Plate
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2-8°C
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25 each (1 each)
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Diluent Assembly 8 (includes Diluent 40 – 25 mL, Diluent 42 – 50 mL)
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≤-10°C
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5 each
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RT
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5 each (100 mL)
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RT
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5 each (50 mL)
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Blocker H, 100 mL
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RT
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5 bottle (100 mL)
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Title
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Journal
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Year
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Reliability of self-sampling for accurate assessment of respiratory virus viral and immunologic kinetics
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Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu
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Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy
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Cytokine biomarkers in tear film for primary open-angle glaucoma
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A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.
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View All
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Product Inserts
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Product Highlights
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Certificate of analysis
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View More
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SDS
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Order Details
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Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
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