V-PLEX Plus NHP MIP-1β Kit

MIP-1β (CCL4)—also known as lymphocyte activation gene 1 protein (LAG-1), G-26 T-lymphocyte-secreted protein, HC21, PAT 744, protein H400, SIS-gamma, small-inducible cytokine A4, and T-cell activation protein 2 (ACT-2)—is a protein that binds to CCR5. CCR5 is shared between MIP-1β, MIP-1α, RANTES, and CCL3L1. MIP-1β is one of the major HIV suppressive factors produced by CD8+ T cells. It down-modulates the expression of CCR5 and thus inhibits the CCR5-mediated entry of HIV-1 into T-cells. MIP-1β occurs as a homodimer and as a heterodimer with MIP-1α. In addition to its involvement in HIV infection, MIP-1β plays a role in large granular lymphocyte leukemia and organ transplant rejection. The NHP MIP-1β Kit provides assay-specific components for the quantitative determination of endogenous MIP-1β in non-human primate urine, serum, plasma, and cell culture supernatants.

  • Specifications
  • Kit Contents
  • References
  • Resources
Order Details
Catalog No
Price in USD
1 plate
5 plates
25 plates
Customer Service/Orders

Scientific/Technical Support

Instrument Support

Company Headquarters