V-PLEX Plus Mouse MIP-1α Kit


V-PLEX Plus Mouse MIP-1α Kit Overview
The V-PLEX Plus Mouse MIP-1α Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse MIP-1α Kit enables the sensitive detection of native MIP-1α in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Plus Mouse MIP-1α assay is also available in a multiplex combination with other related cytokines in the V-PLEX Cytokine Panel 1 (mouse) Kit (catalog # K15245G, K15245D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis. V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX Plus Mouse MIP-1α Assay Features
  • Validated to measure mouse MIP-1α in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.081 pg/mL – 390 pg/mL
  • LLOQ: 0.378 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Plus Mouse MIP-1α assay were assessed and representative data are presented below.

Figure 1. V-PLEX Plus Mouse MIP-1α Calibration Curve
Mouse MIP-1α Calibrator Curve
Figure 2. V-PLEX Plus Mouse MIP-1α Data
Mouse MIP-1α Calibrator Curve Data
MIP-1α Analyte

Description - Mouse macrophage inflammatory protein 1α (CCL3, GOS19-1, SCYA3; Gene ID: 20302) is a chemokine with inflammatory and chemotactic properties. It attracts T cells, B cells, monocytes, and eosinophils. MIP-1α binds to CCR1, CCR4, and CCR5, and like MIP-1β, it is one of the major HIV suppressive factors produced by CD8+ T cells. MIP-1α also induces mast cell degranulation and NK cell activation.

Disease Focus - Multiple myeloma, breast cancer, cystic fibrosis, and sepsis.

Application Area - Inflammation, cytokines, and chemokines

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25 plates
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