Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the
U-PLEX Mouse IL-16 Assay.
V-PLEX Plus Mouse IL-16 Kit Overview The V-PLEX Plus Mouse IL-16 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse IL-16 Kit enables the sensitive detection of IL-16 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays
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The V-PLEX Mouse IL-16 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.
V-PLEX Mouse IL-16 Assay Features - Validated to measure mouse IL-16 in serum, plasma, urine, and cell culture supernatant
- Dynamic range: 4.65 – 1,800 pg/mL
- LLOQ: 15.0 pg/mL
Typical Data Calibration curve for the V-PLEX Plus Mouse IL-16 Kit was assessed and representative data is presented below.
Figure 1. V-PLEX Plus Mouse IL-16 Kit Calibration Curve 
IL-16 Analyte
Description - Mouse IL-16 (LCF), is a 141.8 kDa tetrameric protein. It’s expression by CD4+ and CD8+ cells is enhanced from exposure to antigens or mitogens. IL-16 stimulates lymphocytes, monocytes, and eosinophils through CD4 receptor which signals through intracellular increases of Ca and IP3, and activates the production of IL-2 and IL-15. It is involved in chemotaxis and regulation of transcription.
Disease Research Area - Autoimmune & Inflammation
Application Area - Cytokines & Chemokines, Inflammatory Injury