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Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the
U-PLEX Biomarker Group 1 (ms) 29-Plex.
V-PLEX Mouse Cytokine 29-Plex Overview The V-PLEX Mouse Cytokine 29-Plex is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse Cytokine 29-Plex includes 29 key analytes that are important in inflammation response and immune system regulation as well as numerous other biological processes. To learn more about the advantages of V-PLEX assays
click here.
V-PLEX Mouse Cytokine 29-Plex Features - Validated to measure 29 cytokine markers in serum, plasma, cell culture supernatants, PBMCs, and urine
- Easily customized to create subset multiplexes via the V-PLEX Assay Designer
Typical Data Calibration curve accuracy and precision for each analyte in the V-PLEX Mouse Cytokine 29-Plex were assessed and the representative data are presented below.
Figure 1. V-PLEX Mouse Cytokine 29-Plex Data 
Description
The 29 assays in the V-PLEX Mouse Cytokine 29-Plex are provided in three multiplex panels— Proinflammatory Panel 1 (mouse), Cytokine Panel 1 (mouse) and Th17 Panel 1 (mouse). The panels are optimized to achieve the highest level of performance from each assay, providing efficient biomarker screening and profiling without compromising performance. These panels are composed of assays against mouse cytokines and chemokines that are involved in many biological processes such as inflammation, the Th1/Th2 pathway, chemotaxis, the Th17 pathway, angiogenesis, and immune system regulation. As a result of their association with such a wide number of diseases, these assays are the subject of drug discovery projects, diagnostics development, and basic research. The 29-plex panel can be initially used as a screening panel to identify relevant biomarkers that can then be assembled into a custom panel for long-term studies.
Disease Research Area
Wide ranging, including autoimmune conditions, cancer, intestinal inflammation, obesity, heart disease, asthma, cardiovascular disease, bacterial infections, and fungal infections.
Application Area
Inflammation, cytokines, and chemokines
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Specifications
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Documentation
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References
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Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-15, IL-16, IL-17A, IL-17A/F, IL-17C, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27p28/IL-30, IL-31, IL-33, IP-10, KC/GRO, MCP-1, MIP-1α, MIP-2, MIP-3α, TNF-α
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Species
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Mouse
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Plate Type
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96-well
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Instrument(s)
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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MESO QuickPlex SQ 120
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SECTOR Imager 6000
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SECTOR Imager 2400
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Sample Type
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Cell Culture Supernatant, Rodent Plasma, Rodent Serum, Urine
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Title
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Journal
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Year
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A phase 1 study of prophylactic anakinra to mitigate ICANS in patients with large B-cell lymphoma
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Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke
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Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms
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Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations
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Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection
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Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters