V-PLEX Human TSLP Kit Overview
The V-PLEX Human TSLP Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Human TSLP Kit enables the sensitive detection of native TSLP in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Human TSLP assay is also available in a multiplex combination with other related cytokines in the V-PLEX Cytokine Panel 2 (human) Kit (catalog # K15084G, K15084D).

V-PLEX Human TSLP Assay Features
  • Validated to measure human TSLP in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.063 pg/mL – 325 pg/mL
  • LLOQ: 0.460 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Human TSLP assay were assessed and representative data are presented below.

Figure 1. V-PLEX Human TSLP Calibration Curve
Human TSLP Calibrator Curve
Figure 2. V-PLEX Human TSLP Data
Human TSLP Calibrator Curve Data
TSLP Analyte

Description - Human TSLP is a hemopoietic cytokine that is similar in biological activity to IL-7. It plays an important role in the maturation of T-cells and is expressed primarily by the heart and liver. TSLP binds to a heterodimeric receptor consisting of IL-7Rα and TSLPR on myeloid cells inducing the release of T cell-attracting chemokines from monocytes and enhancing the maturation of CD11c+ dendritic cells.

Disease Research Focus - Strongly correlated with asthma pathogenesis; atopic dermatitis, eosinophilic esophagitis, allergic rhinoconjunctivitis.

Application Area - Inflammation, cytokines, and chemokines

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25 plates
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