U-PLEX Mouse IL-33 Assay


U-PLEX Mouse IL-33 Assay Overview
The U-PLEX Mouse IL-33 Assay maximizes your flexibility to design an experiment that measures IL-33 alone or multiplexed with MSD U-PLEX assays, your own antibody pairs, or a combination of both. U-PLEX assays demonstrate high sensitivity, excellent precision, and up to 5-logs of linear dynamic range. Plates are read in less than 90 seconds on any MSD instrument, using no complicated fluidics or calibration procedures.

U-PLEX Mouse IL-33 Assay Features
  • Simple protocol similar to ELISAs, yet uses less sample
  • Measures mouse IL-33 in serum, plasma, and cell culture supernatants
  • Create custom multiplexes using a selection of U-PLEX assays, your own antibody pairs or both

Assay Format
  • Singleplex – includes MSD GOLD Small Spot Streptavidin Plates
  • Multiplex – includes U-PLEX multiplex plates
  • Both formats use the same assay components for efficient transfer between single- and multiplex configurations.

IL-33 Analyte
Description- Mouse IL-33 (DVS27) is a member of the IL-1 cytokine family, and is structurally similar to IL-1β and IL-18. It is synthesized as a 31 kDa precursor protein that undergoes cleavage by caspase-1 to generate an 18 kDa protein. IL-33 stimulates the production of proinflammatory cytokines as well as TH2 cytokines and chemokines in several immune cell types including mast cells, lymphocytes, basophils, and eosinophils. IL-33 has been shown to reduce the effects of atherosclerosis by the stimulation of TH2 cytokines.

Disease Focus - Pathogenesis of inflammatory conditions including asthma and atopic dermatitis, and rheumatological diseases, including rheumatoid arthritis and systemic lupus erythematosus (SLE).

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Price in USD
1 plate
5 plates
25 plates
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