R-PLEX Human U-PAR Antibody Set

R-PLEX Human U-PAR Antibody Set Overview
The R-PLEX Human U-PAR Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of U-PAR in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human U-PAR Antibody Set Features
  • Measures human U-PAR in plasma
  • Dynamic range: 5.0 - 25,000 pg/mL
  • Median LLOD: 5.0 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human U-PAR Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Human U-PAR Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human U-PAR Antibody Set
U-PAR Analyte

Description - Urokinase Plasminogen Activator Receptor (U-PAR, uPAR, CD87, PLAUR) is a receptor for urokinase-type plasminogen activator (uPA). U-PAR also recognizes vitronectin and some members of the integrin family, with lower affinity. It localizes uPA proteolysis activity to the cell membrane, which is important for wound healing. The uPA:U-PAR system is frequently upregulated in tumors, making it a possible target for anti-metastatic research. uPA:U-PAR interaction can also affect gene expression and chemotaxis.

Disease Research Area - Oncology

Application Area - Oncology & Cancer

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5 plate size
50 plate size
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